diff --git a/srcpkgs/webkit2gtk/patches/musl-ctype_h.patch b/srcpkgs/webkit2gtk/patches/musl-ctype_h.patch
new file mode 100644
index 00000000000..84fd7606763
--- /dev/null
+++ b/srcpkgs/webkit2gtk/patches/musl-ctype_h.patch
@@ -0,0 +1,11 @@
+--- Source/WTF/wtf/DisallowCType.h
++++ Source/WTF/wtf/DisallowCType.h
+@@ -40,7 +40,7 @@
+ // are used from wx headers. On GTK+ for Mac many GTK+ files include <libintl.h>
+ // or <glib/gi18n-lib.h>, which in turn include <xlocale/_ctype.h> which uses
+ // isacii(). 
+-#if !(OS(DARWIN) && PLATFORM(GTK)) && !PLATFORM(EFL) && !defined(_LIBCPP_VERSION)
++#if !(OS(DARWIN) && PLATFORM(GTK)) && !PLATFORM(EFL) && !defined(_LIBCPP_VERSION) && defined(__GLIBC__)
+ 
+ #include <ctype.h>
+ 
diff --git a/srcpkgs/webkit2gtk/patches/musl-execinfo.patch b/srcpkgs/webkit2gtk/patches/musl-execinfo.patch
new file mode 100644
index 00000000000..fbd4472d0c4
--- /dev/null
+++ b/srcpkgs/webkit2gtk/patches/musl-execinfo.patch
@@ -0,0 +1,38 @@
+There is no execinfo.h in musl. Disable backtrace code if
+__GLIBC__ is not defined.
+
+--- Source/WTF/wtf/Assertions.cpp
++++ Source/WTF/wtf/Assertions.cpp
+@@ -71,8 +71,10 @@
+ #if OS(DARWIN) || (OS(LINUX) && !defined(__UCLIBC__))
+ #include <cxxabi.h>
+ #include <dlfcn.h>
++#if defined(__GLIBC__)
+ #include <execinfo.h>
+ #endif
++#endif
+ 
+ extern "C" {
+ 
+@@ -225,7 +227,7 @@
+ 
+ void WTFGetBacktrace(void** stack, int* size)
+ {
+-#if OS(DARWIN) || (OS(LINUX) && !defined(__UCLIBC__))
++#if OS(DARWIN) || (OS(LINUX) && defined(__GLIBC__))
+     *size = backtrace(stack, *size);
+ #elif OS(WINDOWS)
+     // The CaptureStackBackTrace function is available in XP, but it is not defined
+index 657ced4..ceb9c47 100644
+--- Source/JavaScriptCore/inspector/JSGlobalObjectInspectorController.cpp
++++ Source/JavaScriptCore/inspector/JSGlobalObjectInspectorController.cpp
+@@ -46,7 +46,9 @@
+ 
+ #include <cxxabi.h>
+ #include <dlfcn.h>
++#if defined(__GLIBC__)
+ #include <execinfo.h>
++#endif
+ 
+ #if ENABLE(REMOTE_INSPECTOR)
+ #include "JSGlobalObjectDebuggable.h"
diff --git a/srcpkgs/webkit2gtk/patches/musl-isnan.patch b/srcpkgs/webkit2gtk/patches/musl-isnan.patch
new file mode 100644
index 00000000000..7d66bc76c43
--- /dev/null
+++ b/srcpkgs/webkit2gtk/patches/musl-isnan.patch
@@ -0,0 +1,39 @@
+Explicitly use std::isnan() for musl libc
+
+--- Source/WTF/wtf/Stopwatch.h
++++ Source/WTF/wtf/Stopwatch.h
+@@ -44,7 +44,7 @@
+ 
+     double elapsedTime();
+ 
+-    bool isActive() const { return !isnan(m_lastStartTime); }
++    bool isActive() const { return !std::isnan(m_lastStartTime); }
+ private:
+     Stopwatch() { reset(); }
+ 
+@@ -60,14 +60,14 @@
+ 
+ inline void Stopwatch::start()
+ {
+-    ASSERT_WITH_MESSAGE(isnan(m_lastStartTime), "Tried to start the stopwatch, but it is already running.");
++    ASSERT_WITH_MESSAGE(std::isnan(m_lastStartTime), "Tried to start the stopwatch, but it is already running.");
+ 
+     m_lastStartTime = monotonicallyIncreasingTime();
+ }
+ 
+ inline void Stopwatch::stop()
+ {
+-    ASSERT_WITH_MESSAGE(!isnan(m_lastStartTime), "Tried to stop the stopwatch, but it is not running.");
++    ASSERT_WITH_MESSAGE(!std::isnan(m_lastStartTime), "Tried to stop the stopwatch, but it is not running.");
+ 
+     m_elapsedTime += monotonicallyIncreasingTime() - m_lastStartTime;
+     m_lastStartTime = NAN;
+@@ -75,7 +75,7 @@
+ 
+ inline double Stopwatch::elapsedTime()
+ {
+-    bool shouldSuspend = !isnan(m_lastStartTime);
++    bool shouldSuspend = !std::isnan(m_lastStartTime);
+     if (shouldSuspend)
+         stop();
+ 
diff --git a/srcpkgs/webkit2gtk/patches/musl-malloc_trim.patch b/srcpkgs/webkit2gtk/patches/musl-malloc_trim.patch
new file mode 100644
index 00000000000..2bd46816ecc
--- /dev/null
+++ b/srcpkgs/webkit2gtk/patches/musl-malloc_trim.patch
@@ -0,0 +1,15 @@
+There is no malloc_trim() in musl libc
+
+--- Source/WebCore/platform/linux/MemoryPressureHandlerLinux.cpp
++++ Source/WebCore/platform/linux/MemoryPressureHandlerLinux.cpp
+@@ -206,8 +206,10 @@
+ 
+ void MemoryPressureHandler::platformReleaseMemory(bool)
+ {
++#if defined(__GLIBC__)
+     ReliefLogger log("Run malloc_trim");
+     malloc_trim(0);
++#endif
+ }
+ 
+ void MemoryPressureHandler::ReliefLogger::platformLog()
diff --git a/srcpkgs/webkit2gtk/template b/srcpkgs/webkit2gtk/template
index 11c9aab119f..58bded1cfe2 100644
--- a/srcpkgs/webkit2gtk/template
+++ b/srcpkgs/webkit2gtk/template
@@ -1,7 +1,7 @@
 # Template file for 'webkit2gtk'
 pkgname=webkit2gtk
 version=2.8.3
-revision=1
+revision=2
 build_style=cmake
 configure_args="-DPORT=GTK -DENABLE_GTKDOC=OFF -DCMAKE_LINKER=${XBPS_CROSS_TRIPLET}-gcc"
 short_desc="GTK+3 port of the WebKit2 browser engine"
@@ -29,6 +29,11 @@ build_options="gir wayland x11"
 build_options_default="wayland x11"
 if [ -z "$CROSS_BUILD" ]; then
 	build_options_default+=" gir"
+else
+	# Make cmake detect Ruby headers in cross base
+	configure_args+=" -DRUBY_CONFIG_INCLUDE_DIR=${XBPS_CROSS_BASE}/usr/include/ruby-2.2.0"
+	# Fix non-working target CPU detection
+	configure_args+=" -DCMAKE_SYSTEM_PROCESSOR=${XBPS_TARGET_MACHINE%-musl}"
 fi
 
 if [ "$build_option_gir" ]; then
@@ -36,6 +41,7 @@ if [ "$build_option_gir" ]; then
 	hostmakedepends+=" gobject-introspection"
 else
 	configure_args+=" --disable-introspection"
+	configure_args+=" -DENABLE_INTROSPECTION=0"
 fi
 
 if [ "$build_option_wayland" ]; then